To develop an an understanding of molecular mecahnisms of gene expression regulation in eukaryotes. the topics we will cover are:
Chapter 4 Content of Genome Chapter 5 Genome sequences and evolution
Chapter 9,10,11. DNA replication (+ read chapter 10 (Klug) for prokaryotes)
Chapter 13-16. Homologous and site-specific recombination, Somatic DNA recombination
Chapter 14. DNA repair
Chapter 15. Transposable elements and retroviruses
Chapter 18. Eukaryotic transcription (+ read Chapter 17 for prokaryotes)
Chapter 19. Splicing and processing
Chapter 20. mRNA stability and localization
Chapter 21/29. Catalytic RNA and Non-coding RNA
Chapter 22/23. Translation (eukaryotic) Chapter 26 Eukaryotic gene regulation (+ read Chapter 24 for prokaryotes)